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Neurulation and Early Neural Development

Explain neurulation and the early development of the nervous system and define the roles of neuroectoderm and neural crest cells in nervous system development. Understand the time line and the importance of the notochord, neural plate, and neural groove in the formation of the neural tube. Describe formation of primary and secondary brain vesicles in the fifth week.  Note the closure of the neural tube at the anterior and posterior neuropores in the fourth week. Describe the types of neural tube defects (spinal bifida and anencephaly).



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