Antibodies and Humoral Immunity
You do not have access to this note.
Size and complexity to be recognised (an immunogen)
Antibodies as 'tags'
Blastogenesis- Burst of proliferation
Secrete antibody of IgM or IgD at the rate of thousands of molecules per second
Only IgM and IgD can be produced
Short lifespan of the mature B lymphocyte
IgM- Macroglobulin (biggest)- pentamere (five monomers joined by J chain)- Epitopes- Intravascularly- Valence of 10- Highest avidity- Activator of compliment - No free tail (Fc) - CD16- cannot act as an Opsonin
Affinity- biding strength
As the proliferating B cells - centre of the clone- follicular dendritic cells and TH cells
There was a problem reporting this post.
Please confirm you want to block this member.
You will no longer be able to:
Please note: This action will also remove this member from your connections and send a report to the site admin. Please allow a few minutes for this process to complete.